Anti-cancer therapies aimed at blocking mitochondrial energy generation may have wider effects on cancer cell behaviour than just preventing proliferation, new Cambridge research into brain development and tumours in the fruit fly suggests. Cancer cells were once thought to rely on sugar as the primary fuel for their growth, a phenomenon known as the Warburg effect. More recently, it has become clear that other energy sources may be equally important, and much of the growth in cancer cells is fuelled by mitochondria, the powerhouses of cells.
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