Medical World News Inside the Practice: CancerNetwork and Jeffery Auletta, MD, Discuss Mismatched and Unrelated Donor Stem Cell Transplants in…
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CancerNetwork spoke with Jeffery Auletta, MD, about how the Be The Match foundation is using research initiatives to expand eligibility for stem cell transplants in for patient with acute leukemias and myelodysplastic syndrome. For the latest installment of the Inside the Practice Segment of the Medical World News broadcast, CancerNetwork spoke with Jeffery Auletta, MD, senior vice president of Patient Outcomes and Experience for the National Marrow Donor Program/Be The Match and chief scientific director of the Center for International Blood and Marrow Transplant Research/National Marrow Donor Program/Be The Match, about finding donors for patients requiring stem cell transplant.

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John Theurer Cancer Center Investigators Participated in ZUMA-7 Study Showing Value of CAR T-Cell Therapy as Second-Line Treatment for Relapsed Large…
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Newswise HACKENSACK, N.J. (DATE TK) A new study has found that using CAR T-cell therapy as the second line of treatment for diffusing large B-cell lymphoma (DLBCL) that has returned or continued to grow after initial treatment was more effective than the standard second-line regimen of care for improving event-free survival (EFS / defined as disease progression, needing to start a new lymphoma treatment, or death from any cause)

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UMD receives funding to enhance quality of pork production through improved muscle growth in pigs – News-Medical.Net
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The University of Maryland (UMD) received funding from the United States Department of Agriculture National Institute of Food and Agriculture (USDA-NIFA) to enhance the overall quality and efficiency of pork production through improved muscle growth in pigs. While early life nutrition seems to be especially important for how muscles grow and develop, less is known about how these benefits can be passed from mother to child during pregnancy

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Scientists publish perspective on boosting stem cell immunity to viruses – UC Riverside
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Two scientists at UC Riverside have penned a perspective, by invitation from Science magazine, on a new research article authored by researchers at a British lab. Their work discovered a new isoform of Dicer enzyme that protects mouse and human stem cells from several RNA viruses like Zika and SARS-CoV-2 by enhancing antiviral RNA interference, or RNAi, said Shou-wei Ding, a professor of microbiology and plant pathology, who wrote the perspective along with Shabihah Shahrudin, his postdoctoral researcher. An isoform is a protein that functions similarly to another protein, with possibly small differences in their sequences

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Real-World Treatment Patterns and Outcomes in MCL Contrast With Clinical Trials – Targeted Oncology
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Findings of a retrospective real-world analysis of 3455 adult patients treated between January 2011 and November 2020 show that patients in the real world fare worse than those treated in prospective clinical trials. These results underscore the need to develop novel therapies that can be delivered effectively in the community setting, according to Peter Martin, MD, who presented the data during the European Hematology Association (EHA) Congress 2021. The patient population retrospectively evaluated included 1,036 patients under the age of 65 and 1,910 who were 65 years of age or older.

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The Stem Cell Theory of Cancer | Ludwig Center | Stanford …
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Research has shown that cancer cells are not all the same. Within a malignant tumor or among the circulating cancerous cells of a leukemia, there can be a variety of types of cells. The stem cell theory of cancer proposes that among all cancerous cells, a few act as stem cells that reproduce themselves and sustain the cancer, much like normal stem cells normally renew and sustain our organs and tissues.

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