Anti-inflammatory therapies could be effective at preventing heart disease in patients with clonal hematopoiesis, a common age-related blood condition, according to a new study published in Nature. The researchers identified how clonal hematopoiesis worsens atherosclerosis, and their findings suggest that an anti-inflammatory drug previously tested in a broader population of patients with cardiovascular disease may have potential for patients with atherosclerotic heart disease and clonal hematopoiesis. Thought to occur in roughly 10% of people over 70 years of age, clonal hematopoiesis occurs when hematopoietic stem cells (HSCs) acquire mutations.
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