CAR T-Cell Therapy Enters the Arena in Multiple Myeloma With Ongoing Research Ahead – OncLive

The FDA approval of idecabtagene vicleucel (ide-cel; Abecma) has established a role for CAR T-cell therapy in heavily pretreated, relapsed/refractory multiple myeloma, with the product showing an unprecedented response rate and a generally favorable safety profile, said Saad Z. Usmani, MD, FACP. However, with additional BCMA-directed constructs, allogeneic CAR T-cell products, and bispecific antibodies in the pipeline, ide-cel could become just 1 of many novel options the field.

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Researchers Receive Grant to Improve Cellular Therapies to Treat ‘Incurable’ Diseases – University of Arkansas Newswire

Photo Submitted Left: Jorge Almodovar, Right: Raj Rao Two U of A researchers received a $480,000 National Science Foundation grant to investigate how engineered coatings that imitate the tissue matrixsurroundingcells would affect the behavior of therapeutic human mesenchymal stromal cells, or hMSCs. Jorge Almodovar, assistant professor of chemical engineering, and Raj Rao, professor and head of the Department of Biomedical Engineering, were awarded the grant from the NSF Division of Chemical, Bioengineering, Environmental, and Transport Systems. The grant will support research to explore how the extracellular matrix mimetic coatings affect the behavior of therapeutic hMSCs

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Lonza Celebrates 20th Anniversary of Nucleofector Cell Transfection Platform – Technology Networks

2021 marks the 20th anniversary of Lonzas groundbreaking Nucleofector Technology, the industrys leading non-viral cell transfection method, which has been cited more than 10,000 times, including in research by two Nobel Laureates. The innovative Nucleofector Technology enables the transfer of nucleic acids and proteins directly into the cells nuclei by combining optimized electrical parameters and cell type-specific solutions.

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