Mesenchymal stromal cells: Biology of adult mesenchymal stem cells …

Friedenstein AJ, Chailakhjan RK, Lalykina KS: The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet. 1970, 3: 393-403. CAS PubMed Google Scholar Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science

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Research to Boost Bone Formation Informs Orthopaedic Treatments

By Jenni Weems on 10/27/2016 For orthopaedic surgery researcher Mei Wan, advancing anabolic treatments in osteoporosis and bone fracture repair is the long-term goal of her research on bone marrow mesenchymal stem cells (MSCs). Her core focus is identifying mechanisms that determine the multiple lineage differentiation potential of MSCs, particularly those that give rise to bone-making osteoblasts

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Garza Laboratory – Johns Hopkins Medicine

Welcome to the Garza Laboratory! We are fascinated by questions of developmental biology, such as how a single cell has the instructions to build an entire organism. How these embryonic developmental patterns are reinitiated in adults is a central question for regenerative medicine and might eventually lead to insights on how to trigger the regrowth of a severed human limb, for example.

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