Induced Pluripotent Stem Cells: Problems and Advantages when Applying …

Abstract Induced pluripotent stem cells (iPSCs) are a new type of pluripotent cells that can be obtained by reprogramming animal and human differentiated cells. In this review, issues related to the nature of iPSCs are discussed and different methods of iPSC production are described. We particularly focused on methods of iPSC production without the genetic modification of the cell genome and with means for increasing the iPSC production efficiency. The possibility and issues related to the safety of iPSC use in cell replacement therapy of human diseases and a study of new medicines are considered

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What are Induced Pluripotent Stem Cells? | ISCRM

Induced pluripotent stem cell technology is a powerful tool that scientists at the Institute for Stem Cell and Regenerative Medicine use to study a wide range of diseases. To understand the usefulness of induced pluripotent stem cells, it helps to know a few basic facts about stem cells and the role they play in research. There are many types of stem cells. In general, the term stem cell refers to a category of cells that give rise to other cells (like skin, blood, heart, and muscle cells) by replicating and differentiating in response to chemical cues

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Induced pluripotent stem cells, a giant leap for mankind therapeutic …

Abstract Induced pluripotent stem cells (iPSC) technology has propelled the field of stem cells biology, providing new cells to explore the molecular mechanisms of pluripotency, cancer biology and aging. A major advantage of human iPSC, compared to the pluripotent embryonic stem cells, is that they can be generated from virtually any embryonic or adult somatic cell type without destruction of human blastocysts

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