Science and research have always relied on using animals to understand various human diseases. The primarily reasons have been the genetic similarity between animals and humans (mice share 98% of DNA with us), and that we have developed tools to edit genes in various animals.
Ruxolitinib has proven itself a stellar moneymaker for Incyte and Novartis, and it should come as no surprise that the drugs efficacy reached expectations in yet another Phase III trial.
The perfect balance of the stack. The fusion of equilibrium and irregularity. How the stones come from nature yet stand apart
Goosebumps are a weird quirk of our bodies that science doesnt fully understand. Now, researchers at Harvard have uncovered a biological reason for the reaction: its our bodies way of stimulating stem cells to drive new hair growth. Were all familiar with goosebumps
This post was contributed by a community member. Celltex Therapeutics hosts webinar on life-changing mesenchymal stem cell banking and therapy Webinar to be hosted Wednesday, July 29 WHAT: Celltex Therapeutics, a Houston-based biotechnology company, will host a free virtual webinar Wednesday, July 29, 2020 about the benefits of utilizing your own mesenchymal stem cells (MSCs) and how they can lead to proven results and an improved quality of life.
The bioreactors market was valued at US$ 2,958. 50 million in 2019 and is projected to reach US$ 5,169
Madhukar Saxena,1,* Daoud Ali,2,* Dinesh Raj Modi,1 Mohammed HA Almarzoug,2 SA Hussain,2 S Manohrdas2 1Department of Biotechnology, Babasaheb Bhimrao Ambedkar University, Lucknow, India; 2Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia *These authors contributed equally to this work Correspondence: Madhukar SaxenaDepartment of Biotechnology, Babasaheb Bhimrao Ambedkar University, Vidya Vihar, Rai Bareilly Road, Lucknow, IndiaEmail madhukarbio@gmail.com Introduction: TNF-, a proinflammatory cytokine secreted by activated immune cells, and overexpression of it in adipocytes, has an important role in insulin resistance progression and diabetes development.Aim and Objective: Subcutaneous adipocytes derived from mesenchymal stem cells were used for in vitro analysis to find the role of antidiabetic drugs on TNF- in high glucose-fed adipocytes.Methods: In vitro adipocytes were used along with variable concentration of anti-diabetic drugs. The level of TNF- was measured by ELISA and the mRNA level was quantified using SYBR-Green real-time PCR. All data were statistically analyzed.Results: The level of TNF- and the mRNA expression were observed and analyzed with normal adipocytes.
Robert Millman co-founded and led Semma Therapeutics as CEO while also a managing director of MPM Capital. By the time he left the stem cell therapy pioneer two years before it would be sold to Vertex he had left VC life behind. Instead, he went around scouting new technologies, visiting with tech transfer offices and academics in the Boston/Cambridge area to find worthy ideas that could benefit from his IP expertise.
This article explains some of the terminology relating to advanced therapy medicinal products (ATMPs), including gene and cell-based therapies, tissue-engineered products, and combined ATMPs.
The Covid-19 pandemic is one of the greatest challenges modern medicine has ever faced. Doctors and scientists are scrambling to find treatments and drugs that can save the lives of infected people and perhaps even prevent infection.
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