Coronavirus: Stem Cell Contract Manufacturing Demand to Surge Rapidly | Roots Analysis – The Think Curiouser

As is the case with numerous pharmaceutical companies who have been racing to find a potential cure for the patients suffering from infection with Corornavirus, the stem cell industry has been on an outlook to identify stem cell therapies which can treat the disease and / or its symptoms.

Athersys is developing a possible therapy for acute respiratory distress syndrome (ARDS). It is among the most concerning complication caused by COVID-19. Further, the firm has announced that they have made an attempt to fast track the launch of a pivotal trial of its MultiStem off-the-shelf stem cell product. Similarly, San Marinos Bioscience Institute recently announced that mesenchymal stem cells could be potential treatment options for COVID-19. The university claims that mesenchymal stem cells have the ability to improve lung microenvironment. The transplanted cell also promotes healing of the tissues and prevent pulmonary fibrosis.

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Further, the Chinese open repository for scientific researchers says that, currently, 14 clinical trials to treat coronavirus patients are being conducted in China after some evidence of positive result in the animal models. Preclinical studies on animal models have shown signs of repair in severe organ damage caused by the virus. Additionally, it is worth mentioning that the organisation indicates that if the therapy is a success, then individuals suffering from the COVID-19 can utilise their own stem cells obtained from fat cells (autologous therapy). However, the expansion of these cells for infusion will correspond to 1 million cells per kg of weight, which will require a time span of one to two weeks.

The increasing activity in the R&D of stem cell therapies has somewhat made it difficult for industry stakeholders to establish in-house manufacturing, especially for the large-scale manufacturing. These challenges are likely to lead to an increased dependence on contract manufacturing service providers.

Do We Have Enough Manufacturing Capacity?

With the virus strengthening its foothold in several countries across the globe, the threat of pandemic has become real and the question is are we ready?

Even if these therapies are approved, do we have the capacity to manufacture it on the global basis?

Roots Analysis, in its recent report, has estimated the global stem cell therapy capacity. To know further about the capacity, check out the report here

Expert Opinion

In the report, Roots Analysis has identified several parameters which is necessary to select and monitor the capabilities / performance of their CMO partners.

For further information on this emerging domain, check out the report here.

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Coronavirus: Stem Cell Contract Manufacturing Demand to Surge Rapidly | Roots Analysis - The Think Curiouser